I've been having this issue for a while with my USB optical mouse in which the pointer will suddenly jump all over the screen. It even happens while I am playing games. For instance, I might be playing a first person shooter and all of a sudden I'm staring at the sky and spinning around in circles. It will continue to do this until I move the mouse around a lot. These occurrences are also becoming more frequent and intense to the point of being intolerable. I've tried a number of things in attempting to correct this problem, but nothing seems to work. Any ideas?
Is this mouse Wired, or Wireless?
Try changing your mouse mat, I used to have the problem, and it was my mouse mat.