An attempt to create a Woolly Mammoth clone 28 replies

Please wait...

Commissar MercZ

Notable Loser

300,005 XP

29th January 2005

0 Uploads

27,113 Posts

0 Threads

#1 6 years ago

There has been news that this a scientific team will try to clone a wolly mammoth. This will take place by using remains of a Mammoth found in Siberia and having the Korean cloning team attempt to restore cells to be used in cloning, by way of a surrogate elephant.

First a plant from the past sprouted new life — now researchers in Russia and South Korea are moving forward with a plan to resurrect the Ice Age woolly mammoth. Scientists in both countries inked a deal Tuesday to share technology and research that could lead to the birth of a mammoth clone, gestated in a surrogate Indian elephant mother.

Mammoth remains were uncovered in thawed Siberian permafrost, and scientists around the world have been trying to extract DNA from the remains. Previously, paleobiologists were able to reproduce mammoth blood protein, and Japanese researchers want to resurrect the mammoth within five years. This new project will move forward if the Russian institution, the North-Eastern Federal University of the Sakha Republic, can ship its mammoth remains to the Koreans.

The scientists involved include Hwang Woo-Suk of South Korea's Sooam Biotech Research Foundation, who was embroiled in controversy after he was found to have faked some research into human stem cells. He created Snuppy, the world’s first cloned dog, in 2006. Chinese scientists will also be involved in this research, according to AFP.

The plan would work like previous cloning studies that successfully reproduced dogs, a cow, a cat, a pig, a wolf and coyotes. The nuclei of mammoth somatic cells would be implanted into the nuclei of donor elephant eggs, to produce elephant embryos with mammoth DNA. The embryos would then be implanted in elephant wombs, where they would gestate for 22 months. The team plans to use an Indian elephant for the cell nucleus transfer, according to AFP.

The mammoth protein study showed that we can actually learn a fair amount by working with these extinct creatures — the mammoth blood was found to contain an anti-freeze component that no one would have known about had we not recreated its blood. So who knows what we could learn from recreating the whole thing? Surely, nothing could go wrong here ... not at all ... right?

The AFP article

SEOUL — Russian and South Korean scientists have signed a deal on joint research intended to recreate a woolly mammoth, an animal which last walked the earth some 10,000 years ago.

The deal was signed by Vasily Vasiliev, vice rector of North-Eastern Federal University of the Sakha Republic, and controversial cloning pioneer Hwang Woo-Suk of South Korea's Sooam Biotech Research Foundation, on Tuesday.

Hwang was a national hero until some of his research into creating human stem cells was found in 2006 to have been faked. But his work in creating Snuppy, the world's first cloned dog, in 2005, has been verified by experts.

Stem cell scientists are now setting their sights on the extinct woolly mammoth, after global warming thawed Siberia's permafrost and uncovered remains of the animal.

Sooam said it would launch research this year if the Russian university can ship the remains. The Beijing Genomics Institute will also take part in the project.

The South Korean foundation said it would transfer technology to the Russian university, which has already been involved in joint research with Japanese scientists to bring a mammoth back to life.

"The first and hardest mission is to restore mammoth cells," another Sooam researcher, Hwang In-Sung, told AFP. His colleagues would join Russian scientists in trying to find well-preserved tissue with an undamaged gene.

By replacing the nuclei of egg cells from an elephant with those taken from the mammoth's somatic cells, embryos with mammoth DNA could be produced and planted into elephant wombs for delivery, he said.

Sooam will use an Indian elephant for its somatic cell nucleus transfer. The somatic cells are body cells, such as those of internal organs, skin, bones and blood.

"This will be a really tough job, but we believe it is possible because our institute is good at cloning animals," Hwang In-Sung said.

South Korean experts have previously cloned animals including a cow, a cat, dogs, a pig and a wolf.

Last October Hwang Woo-Suk unveiled eight cloned coyotes in a project sponsored by a provincial government.

Maybe it'll fail and nothing will come of it, but still I found it something interesting to think about. Here's a Nature article about the extinct plant that were 'resurrected' from fruit that were buried by squirrels 30,000 years ago that the article mentions at the beginning.




Nittany Tiger Forum Mod

*Shrug*

289,107 XP

15th September 2004

0 Uploads

27,136 Posts

0 Threads

#2 6 years ago

Sounds awesome. Dunno if we'll see an exact Wooly Mammoth out of this since it'll be half-elephant though.




Flash525

The Carbon Comrade

50 XP

14th July 2004

0 Uploads

15,103 Posts

0 Threads

#3 6 years ago
Killer Kyle;5622709Sounds awesome. Dunno if we'll see an exact Wooly Mammoth out of this since it'll be half-elephant though.

This.

It's great and all for them to say they're going to bring the Woolly Mammoth back into existence, but it isn't going to be a Woolly Mammoth, it's going to be a Elephant/Mammoth hybrid of sorts.

Next I'm expecting them to say they're going to try this with T-Rex DNA, though are going to impregnate an iguana with the necessary cells. Cause that'll then be a T-Rex, wont it? :rolleyes:




Nemmerle Forum Mod

Voice of joy and sunshine

298,365 XP

26th May 2003

0 Uploads

28,147 Posts

5 Threads

#4 6 years ago

I don't really see the point - surely there are more interesting ways to play god? Still, I suppose as a tech-demo, of sorts, it's not necessarily a bad thing.




Serio VIP Member

The Dane

149,931 XP

11th November 2006

3 Uploads

12,511 Posts

38 Threads

#5 6 years ago

Any progress is good progress in the field of genetics, and cloning. I'm thinking it's more of a proof of concept - to my knowledge, there has never been a successful cloning of an extinct animal.




Schofield VIP Member

om :A

319,554 XP

24th October 2007

1 Uploads

30,539 Posts

0 Threads

#6 6 years ago

As long as they put it down afterwards.

There's a reason it doesn't exist anymore. It's funny, for a bunch of scientists who probably don't believe in God, they sure want to become one.

That's my reality side speaking, sorry, gtfo.

Ok I think it would be pretty badass if we brought one back, especially if it comes out in such a way where it goes on a rampage and takes down the cloners.




Flash525

The Carbon Comrade

50 XP

14th July 2004

0 Uploads

15,103 Posts

0 Threads

#7 6 years ago

Serio;5622957Any progress is good progress in the field of genetics, and cloning. I'm thinking it's more of a proof of concept - to my knowledge, there has never been a successful cloning of an extinct animal.[/QUOTE]Have there been successful cloning of non-extinct animals? Those few reports I've read on such matters, the cloned animal didn't live very long.

If there was a way to clone animals, or at least parts of them, there would be no more need for mass-butchering. Instead we could just 'create' a steak. There's an idea.

Schofield;5622987As long as they put it down afterwards.[/quote]Why?

[QUOTE=Schofield;5622987]There's a reason it doesn't exist anymore. It's funny, for a bunch of scientists who probably don't believe in God, they sure want to become one.

If you're putting the Mammoth's extinction down to nature, then I would ask what of the Dodo? That wasn't nature, that was us.

Animals from the past become extinct because of the climate ect. Animals of today become extinct because we don't give a damn about the planet, nor it's wildlife.

[QUOTE=Schofield;5622987]Ok I think it would be pretty badass if we brought one back, especially if it comes out in such a way where it goes on a rampage and takes down the cloners.

I'd still much rather see a T-Rex.




Nemmerle Forum Mod

Voice of joy and sunshine

298,365 XP

26th May 2003

0 Uploads

28,147 Posts

5 Threads

#8 6 years ago

Schofield;5622987As long as they put it down afterwards.

There's a reason it doesn't exist anymore.[/QUOTE]

Presumably there's a reason for everything. So, if you use the existence of a reason as a knock-down argument not to change something - and apply that consistently - you'll never do anything.

See also: Hume's Law http://en.wikipedia.org/wiki/Is–ought_problem

Schofield;5622987It's funny, for a bunch of scientists who probably don't believe in God, they sure want to become one.

-shrug- I'm sure we'd all like to be able to justifiably believe in an omnipotent omni-benevolent being. And if you're in the business of progress, it doesn't seem especially surprising that you'd try to move closer to what you'd like.

[QUOTE=Schofield;5622987]That's my reality side speaking, sorry, gtfo.

Ok I think it would be pretty badass if we brought one back, especially if it comes out in such a way where it goes on a rampage and takes down the cloners.

It needs to live long enough for them to mount a giant laser on it. Research shows that all rampages of previously extinct creatures are at least 60% cooler with lasers.




Schofield VIP Member

om :A

319,554 XP

24th October 2007

1 Uploads

30,539 Posts

0 Threads

#9 6 years ago

Why? Because it ultimately serves no purpose, unless they create one of the opposite sex to make them breed. If they start breeding they'll keep breeding, they had their time.

Yeah, we made the Dodos extinct. But this is a Mammoth.

People seem to be pro-extinction when it comes to things that threaten humanity. We forced the smallpox virus into extinction, something which could have thinned our numbers and could have brought balance back into play. Quite foolish to be pro-extinction (not saying you are, Aerilon) for one thing but anti-extinction for another. We will eradicate any threat to us, when we are the threat to everything else on Earth. If I had it my way, there wouldn't be many humans left, just pockets around the globe, and reproduction would happen in intervals, not whenever humans want it. We deserve to survive, but not if it means destroying the thing we live on.

And I would also much rather see a T-Rex.

Edit: WTF happened to my quote tags? Anyway this was directed at you Aerilon. =p

@Nemmerle, I didn't mean some sort of divine reason - the reason I was talking about was the climate, they didn't adapt to it.




redgroupclan

is gay.

50 XP

16th August 2008

0 Uploads

15,616 Posts

0 Threads

#10 6 years ago

Got disappointing after the elephant surrogate part.